Glaucoma Research Today is a free monthly online journal that collates and summarizes the latest research about Glaucoma, including details on cataracts, surgery, treatment, blindness.

Topiramate, pseudotumor cerebri, weight-loss and glaucoma: an ophthalmologic perspective.

Alore PL, Jay WM, Macken MP

Loyola University Medical Center, Maywood, IL 60153, USA.

Approved for the treatment of epilepsy and migraine prophylaxis, topiramate also acts as a carbonic anhydrase inhibitor implying a potential role in the treatment of pseudotumor cerebri (PTC). Topiramate has a propensity to cause anorexia with consequent weight loss, which alone may be curative in PTC. Prescribers must be aware of several reported cases of acute secondary angle-closure glaucoma reported in patients treated with topiramate.

Published 6 March 2006 in Semin Ophthalmol, 21(1): 15-7.
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