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Optical coherence tomography measurement of retinal nerve fiber layer after acute primary angle closure with normal visual field.

Tsai JC

Department of Ophthalmology, Chang Gung Memorial Hospital, 123 Ta-Pei Road, Niao-Sung Hsiang, Kaohsiung County 833, Taiwan. tsai4118@ms26.hinet.net

PURPOSE: To detect retinal nerve fiber layer (RNFL) thickness after a single acute primary angle closure (APAC) attack with normal visual field. DESIGN: Prospective, observational case study. METHODS: Twenty-eight patients who had a single unilateral APAC attack associated with normal visual fields at three months after remission and 28 single eyes from normal controls were enrolled. Duration of APAC attack was 5.9 +/- 2.7 hours. Comparisons of average RNFL thickness and RNFL thickness in four quadrants and in 12-o'clock-hour segments of the attacked eyes, unaffected fellow eyes, and normal controls were made using fast RNFL thickness (3.4) of Stratus optical coherence tomography. RESULTS: Significant differences were demonstrated comparing the inferior-quadrant RNFL thicknesses for the attacked eyes with those of the normal controls (P = .02) and fellow eyes (P = .02) using one-way analysis of variance with Tukey's tests. CONCLUSIONS: Inferior region RNFL thickness was significantly decreased in the attacked eyes after an APAC episode associated with normal visual field.

Published 8 May 2006 in Am J Ophthalmol, 141(5): 970-2.
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